3 in 1 – Candida albicans/ Trichomonas vaginalis/ Gardnerella vaginalis Antigen Combo Test Kit (LFIA).
Candida albicans is a major human fungal pathogen. It exists as a commensal in the oral cavity, intestinal tract or genital tract of most individuals and is limited by the local microbiota, epithelial barriers and immune defenses. Its disruption can lead to fungal overgrowth and the development of mucosal infections such as oropharyngeal or vulvovaginal candidiasis, and patients with compromised immunity are susceptible to life-threatening systemic infections.
Trichomoniasis is a sexually transmitted disease (STI) with important public health implications; it has been associated with vaginitis, cervicitis, urethritis, and pelvic inflammatory disease (PID). Trichomoniasis also affects birth outcomes and is a co-factor in the transmission and acquisition of human immunodeficiency virus (HIV). Trichomonas vaginalis is a motile organism about the size of a white blood cell. It has at least 4 flagella that provide undulating motility. The organism resides in the lumen of the urogenital tract. The organism releases cytotoxic proteins that destroy the epithelial lining. During infection, the vaginal pH usually increases.
Gardnerella vaginalis is an anaerobic bacterium that is part of the normal vaginal flora. Normally, the vaginal flora is dominated by the lactobacilli species, but when organisms such as Gardnerella begin to overgrow and become the dominant species, this leads to bacterial vaginosis (BV).
Bacterial vaginosis is characterized by the presence of clue cells, which are cervical epithelial cells covered with rod-shaped bacteria.
Introduction The Candida albicans/Trichomonas vaginalis/Gardnerella vaginalis Antigen Combo Test Kit (LFIA) is a latex microsphere immunochromatography for the rapid qualitative detection of Candida albicans, Trichomonas vaginalis, and Gardnerella vaginalis in female vaginal swab specimens in vitro. This test kit is suitable for women with clinical symptoms of gynaecological inflammation or suspected gynaecological inflammation.
